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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
35.76
Human Site:
S350
Identified Species:
60.51
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
S350
Q
K
A
G
V
T
R
S
G
R
L
I
L
W
E
Chimpanzee
Pan troglodytes
XP_511801
843
90571
S501
Q
K
A
G
V
T
R
S
G
R
L
I
L
W
E
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
S439
Q
K
A
G
V
T
R
S
G
R
L
I
L
W
E
Dog
Lupus familis
XP_548291
727
78319
S385
Q
K
A
G
V
T
R
S
G
R
L
I
L
W
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
S356
Q
K
A
G
V
T
R
S
G
R
L
I
L
W
E
Rat
Rattus norvegicus
NP_001099274
698
75236
S356
Q
K
A
G
V
T
R
S
G
R
L
I
L
W
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
S334
Q
R
A
G
V
T
K
S
G
R
L
I
I
W
E
Chicken
Gallus gallus
XP_415822
728
79098
S356
Q
K
A
G
V
T
K
S
G
R
L
I
M
W
E
Frog
Xenopus laevis
Q7ZZC8
944
104521
E371
A
V
V
T
V
E
K
E
L
Y
T
W
V
N
M
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
S358
Q
K
M
G
V
T
K
S
G
R
L
I
T
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
N528
I
Q
S
V
G
V
G
N
Y
F
S
V
I
C
C
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
A136
K
I
M
R
G
S
V
A
P
I
S
D
R
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
R296
R
N
S
F
P
E
Q
R
R
R
P
A
G
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
I428
D
F
P
S
T
T
D
I
T
D
I
S
I
A
E
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
86.6
6.6
80
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
20
86.6
N.A.
N.A.
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
58
0
0
0
0
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
15
0
8
0
0
0
0
0
0
72
% E
% Phe:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
65
15
0
8
0
65
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
8
8
65
22
0
0
% I
% Lys:
8
58
0
0
0
0
29
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
65
0
43
0
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
0
8
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
65
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
8
0
0
43
8
8
72
0
0
8
0
0
% R
% Ser:
0
0
15
8
0
8
0
65
0
0
15
8
0
0
15
% S
% Thr:
0
0
0
8
8
72
0
0
8
0
8
0
8
0
0
% T
% Val:
0
8
8
8
72
8
8
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
65
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _